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GE Healthcare SIGNA PET/MR

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The GE Healthcare SIGNA PET/MR is an advanced hybrid imaging system that seamlessly integrates 3.0 T magnetic resonance imaging (MRI) and positron emission tomography (PET) within a single scanner—enabling simultaneous, co-registered acquisition of high-resolution anatomical, functional, metabolic, and molecular information.

  • Magnetic field strength: 3.0 T
  • Gantry aperture: 60 cm
  • Field of view (FOV): 50 cm (spherical)
  • Maximum patient weight: 200 kg
  • Gradients: 44 mT/m amplitude / 200 mT/m/ms slew rate
  • RF channels: Up to 128 for MRI, 32 for PET
  • Magnet type: Superconducting, closed-bore
  • Cooling type: Liquid helium

Type: Tomograph

Country of origin: GE

Brand: SIGNA

Description
Specifications

Description

The GE Healthcare SIGNA PET/MR is an expert hybrid imaging system that integrates 3.0 T MRI and positron emission tomography (PET) in a single scanner, designed for advanced clinical and research applications in oncology, neurology, cardiology, and inflammatory diseases. It enables simultaneous acquisition of high-resolution anatomical, functional, metabolic, and molecular data—without the additional ionizing radiation associated with CT-based hybrid systems.
The system features silicon photomultiplier (SiPM) detectors coupled with 25-mm lutetium-based oxyorthosilicate (LBS) scintillators, delivering exceptional PET sensitivity and full support for Time-of-Flight (TOF) technology. Combined with the Q.Clear reconstruction algorithm—a Bayesian penalized-likelihood method—the system achieves superior signal-to-noise ratio, enhanced lesion detectability, and quantitative accuracy in PET imaging, while maintaining the unparalleled soft-tissue contrast and multiparametric capabilities of 3.0 T MRI.

Specifications

Key Specifications:
  • Magnetic field strength: 3.0 T
  • Gantry aperture: 60 cm
  • Field of view (FOV): 50 cm (spherical)
  • Maximum patient weight: 200 kg
  • Gradients: 44 mT/m amplitude / 200 mT/m/ms slew rate
  • RF channels: Up to 128 for MRI, 32 for PET
  • Magnet type: Superconducting, closed-bore
  • Cooling type: Liquid helium
  • Country of manufacture: USA
  • Warranty: 12 months

Key Technologies and Advantages:
  • Advanced Hybrid PET/MR ImagingTOF + Q.Clear: Time-of-Flight reconstruction combined with Bayesian penalized-likelihood algorithm for superior sensitivity, noise reduction, and quantitative PET accuracy
  • Zero TE (ZTE): Enables MR-based bone imaging without CT or ionizing radiation
  • Simultaneous data acquisition: Perfect spatial and temporal alignment between PET and MRI for precise multimodal correlation
  • Comprehensive Clinical ApplicationsOncology: Quantitative tumor metabolism assessment, therapy response monitoring, and early recurrence detection
  • Neurology: Early diagnosis of neurodegenerative disorders (e.g., Alzheimer’s, Parkinson’s) using amyloid and FDG tracers
  • Cardiology: Evaluation of myocardial viability, inflammation, and infiltrative diseases (e.g., sarcoidosis, amyloidosis)
  • Inflammatory conditions: Precise localization of active disease foci (e.g., in Crohn’s disease)
  • Motion Artifact SuppressionAdvanced motion correction technologies: PROPELLER, PROMO, and Pencil Beam Navigator
  • Compensates for respiratory, peristaltic, and involuntary motion—ensuring diagnostic image quality even in pediatric and unstable patients
  • Research CapabilitiesOrchestra: Direct access to raw k-space and list-mode data for custom reconstruction and algorithm development
  • PET ToolBox: Platform for developing novel PET protocols and radiopharmaceuticals
  • In vivo multinuclear spectroscopy: Real-time investigation of metabolic and biochemical processes (e.g., ³¹P, ¹³C)
  • SIGNA Works Integrated PlatformSpecialized clinical suites: NeuroWorks, OncoWorks, CVWorks, BodyWorks
  • Automated protocols, 3D/4D visualization, and quantitative analytics
  • Full interoperability with DICOM, PACS, and cloud-based ecosystems for seamless workflow integration